Primary Faculty

Abou-Donia, Mohamed B.

Mechanisms of chemically induced neurodegenerative disorders.

Alvarez, James

Intratumor heterogeneity and tumor progression.

Casey, Patrick J.

Currently in Singapore at the Duke University/National University of Singapore's graduate medical school. Cellular signaling mediated through GTP-binding proteins; lipid modification of proteins.

Counter, Christopher

Molecular analysis of Ras signaling in cancer.

Fox, Donald

Organ repair and genome stability.

Goetz, Sarah C.

The role of primary cilia-mediated cell signaling in development and disease.

Haystead, Timothy

Using chemical biology approaches to define novel drug targets for the treatment of hypertension, obesity, cancer, inflammatory disease and infectious disease.

Kastan, Michael

Molecular and cellular responses to DNA damage and other stresses.

Kornbluth, Sally

Molecular mechanisms controlling apoptosis and cell cycle progression.

Kuhn, Cynthia M.

Gonadal steroids and monoamine function in the brain, dopamine and addiction in development

Lew, Daniel J.

Cell cycle control and the control of cell polarity.

Locasale, Jason

Our research uses metabolomics, computational biology, and genomics technologies to study metabolism and its contribution to health and disease

MacAlpine, David

Genomic approaches to understanding how the molecular architecture of the chromosome regulates DNA replication.

Mathey-Prevot, Bernard

Utilizing high throughput cell-based assay to understand how signaling pathway architecture and integration have been hijacked in cancer cells.

McDonnell, Donald P.

Development and application of novel molecular approaches for the discovery of estrogen, progesterone and androgen receptor modulators for use in the treatment of prostate and breast cancer.

Newgard, Christopher B.

Metabolic regulatory mechanisms; Regulation of survival and function of pancreatic islets.

Pendergast, Ann Marie

Regulation of cellular signaling pathways by protein tyrosine kinase networks in normal development and cancer.

Schwartz-Bloom, Rochelle D.

Research and development of novel science education programs that incorporate pharmacology into the K-12 educational arena.

Slotkin, Theodore A.

Effects of endocrine status, environmental toxicants and drugs on brain development; molecular neurobiology of neuronal differentiation.

Thiele, Dennis J.

Stress-responsive gene expression and diseases of protein malfolding; role of copper and iron in signaling, growth and development.

VanDongen, Antonius

Currently in Singapore at the Duke University/National University of Singapore's graduate medical school. Mechanisms underlying processes of learning and memory.

Wang, Xiao-Fan

Mechanisms of TGF-β action and signaling, DNA damage checkpoint, Mechanisms of tumor metastasis.

Wood, Kris

New functional genomics technologies and their applications in basic and translational cancer biology

Yao, Tso-Pang

The role of protein acetylation and deacetylation in growth control and cancer formation.