The Department of Pharmacology and Cancer Biology was created to foster collaborative interactions between scientists with different, though complementary, research interests and expertise. The primary goal in developing such an interdisciplinary department was to create an environment where rigorous scientific debate and discourse between researchers with different perspectives would create a stimulating and productive intellectual environment for faculty and trainees alike. As you browse through the research descriptions of our faculty and appreciate the breadth and significance of their scientific achievements, it should become clear that this experiment was a tremendous success. Research projects address a myriad of important scientific questions relevant to cancer, metabolism, nervous system function, drugs of abuse, and environmental toxicants. However, one unifying theme that has emerged in the department is cell signaling and the use of pharmacological approaches to define the key regulatory steps in relevant pathways that may be amenable to pharmaceutical exploitation or whose dysregulation may be involved in the pathogenesis of disease. It is a privilege to welcome you to our website and we encourage you to learn more about the opportunities in research, training, and education offered by this exciting and dynamic department.
Donald P. McDonnell, Ph.D.
Professor and Chairman


  • Tuesday, September 1, 2015 at 2:00 pm

  • Jacob Mercer (Advisor: Daniel Wechsler)
  • “A Role for PICALM in Macroautophagy and Cellular Cholesterol Homeostasis”
  • 147 Nanaline Duke
  • Wednesday, September 16, 2015 at 12:00 pm

  • Matt Hirschey, PhD, Duke University School of Medicine
  • “Cracking that nut: solving a novel enzymatic activity to learn something about metabolism”
  • 103 Bryan Research
  • Wednesday, September 23, 2015 at 12:00 pm

  • Andrew Thorburn, PhD, University of Colorado Anschutz Medical Campus
  • “Targeting autophagy in cancer”
  • 103 Bryan Research
[ All Upcoming Seminars ]

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